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Type of vaccine
Rabies vaccine (Fig. 4.14) is a killed vaccine. verorab insert
Two types of rabies vaccines are available; cell culture vaccines (CCVs) or Embryonated egg-based vaccine (EEV).

1. Cell Culture Vaccines
a) Human Diploid Cell Vaccine (HDCV), Liquid (Adsorbed), I.M dose; 1ml
b) Purified Chick Embryo Cell Vaccine (PCECV), I.M dose; 1ml
c) Purified Vero Cell Rabies Vaccine (PVRV), I.M. 0.5ml or 1ml (depends on the manufacturer)

Pneumococcal Conjugate Vaccine (PCV)

Pneumococcal Conjugate vaccine has been introduced in the NIS under UIP since May 2017.
In the first phase, the vaccine was rolled out in Himachal Pradesh and parts of Bihar and Uttar Pradesh. Introduction in Madhya Pradesh and Rajasthan will follow and eventually be expanded to the country.

Vaccine Type: killed, conjugate vaccine
13 serotypes are individually conjugated to a nontoxic variant of diphtheria toxin.
It is a liquid preparation. After shaking, the vaccine is a homogenous, white suspension.


Currently, there are three types of JE vaccines in use:
1. The mouse brain-derived inactivated (Killed) vaccine.
2. The cell culture-derived inactivated (Killed) vaccine.
3. The cell culture-derived live, attenuated vaccine using SA 14-14-2 strain of JE virus.
Under the National program, the live attenuated (SA 14-14-2), cell culture-derived vaccine is used in India. It is presently manufactured in P. R. China. It is imported from there for use in India.


Type of vaccine
Killed, recombinant type

Route of administration
Intramuscular injection

0.5 mL till 10 years of age; adult dose: 1 mL


Side effects
Soreness, erythema, induration, fatigue, fever, malaise, influenza-like symptoms.
Less common systemic reactions include nausea, vomiting, diarrhea, abdominal pain, abnormal liver function tests, arthralgia, myalgia, rash, pruritus and, insert


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